A new research has discovered that fats were a ‘new weapon’ in the war against type 2 diabetes and play an important role to treat it. With changing lifestyle patterns, the incidence of lifestyle diseases is also on the rise. Diabetes is one of major lifestyle diseases and according to the WHO statistics of 2012, every 10 persons is diabetic. With such high incidence rates, researchers all across the world are trying to develop new treatment and preventive techniques to curb diabetes. A new study has recently discovered ‘fats’ that play an important role in fighting type 2 diabetes efficiently.
These lipids were the fed to insulin-resistant mice and the researchers found that there had been an improvement in inflammation, insulin sensitivity and glucose uptake. The researchers also measured FAHFA levels in the blood samples from human subjects, and found lower levels of these compounds in those with insulin resistance. Saghatelian said that they would be able to come up with better therapies to treat the disease with fewer side effects and that would be effective to a large number of people.
Using the mass spectrometry technique, researchers identified a total of 16 different types of FAHFAs in the mice. These fats are a new class of potentially therapeutic lipids, called fatty-acid esters of hydroxy fatty acids (FAHFAs). They are usually found in people with insulin resistance. The study was conducted on diabetic mice. The FAHFAs when administered to these mice improved their glucose metabolism and insulin secretion. This finding paved new roads to develop novel therapeutic methods for the treatment of the disease.
Saghatelian said that they would be able to come up with better therapies to treat the disease with fewer side effects and that would be effective to a large number of people.